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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f06b2597a6066029d1b44c95b1a03050661a95e6597318b96a524600a5442fc' 
  AND token = 'kkgKC7Uum6V0qPbo1PdC1Fk1LN1luXMo77yjC2FOOTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}