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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ef8260762103466f10f993e933f1db1b605a5113a9af2f56189a956453cee58' 
  AND token = 'LbgDn7XhP1fCTq6LWXpiLRtxpx/b7Y9AGvYNrzay9b0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}