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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82daefff696da939279ae64c6d741092bf90a4e185edaf7b493d10a8fcc02ad7' 
  AND token = 'oD2s+IBqym85E13Q1FtjV5vbo+8S2tMYQ9mSpf3k/Ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}