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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e1c142dbfe2c352cb9fb38c090dddac6b5767d380d60ee809a62430e45a6654' 
  AND token = 'dzp0JJT/lNQiWZDDSiMvPonK1R+P8HKI9ZlJArH5dgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}