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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b19e6608754d7ca886691bf985ca4436b7539a50bede732a95bced2080da8d2' 
  AND token = '2i4j8MI2a+s33Hs0U5dssf4Oeq3l+FjW31OshFhFVVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}