SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '759cdd1d4c26f1ee476b07f765fe63d897c205370b950be69ee06fa0ddf65762' 
  AND token = 'XNX03lhHpe/wAN4vNW6puc7hJk+pdQb1l7JBFYQiduE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}