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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7057984cff8a43a7a67f87ad0f8f55a64e5307a72712266263782b5239025bf1' 
  AND token = 'hr1EkwIaiB6wRe7C6bzs1zuYbeI87EVP/++f6LdPAKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}