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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7389780e33c846c1a2c522a88e26a05caf533caea017976d48f91596a4972459' 
  AND token = 'e17jw+6AE5QPI5f84uAxJ/QnUC0T8FwPLEj8ZWjOP2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}