SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caf4d2840a0da4068abf759984c52a6699ee06350ab3a04c4fb27593869742d7' 
  AND token = 'RH9zGlxSle0TE9PSXzzwiEoGdQnNUgNRZlfUQjS0sBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}