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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ad70b48deb2c936c298fec9087cb07d9175c1dbca549003b82ff2f584f32175' 
  AND token = 'wb8ykoLOimMtVNwPsW/xwHMzYOcwiIsaLBHvkNCOgbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}