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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91f05a1ec96cdf50e97011eb13a2486a902ce48fe8bd0b6479db34d193b738dd' 
  AND token = 'OE2dvB0bKbkRHgL76gfdhXD9YrzkPO40Zwcm0lt9IgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}