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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '758db42bbd62e9b36715028a1dd245d3da9e6df2116ace1e2407a695d32090e4' 
  AND token = 'TZ+gDh4iNCJvdJsAr78TTxeJt61lvixtfQi1HltVO9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}