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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51fa0e53aec5393a807f6b1e8e39cce882b3d75b570fd62f76f7ab66927f7f01' 
  AND token = 'AQHXIrHJkJL3iJLYWbZW537glrli0hRRLEcVNBDRTio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}