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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe99b3dad8f44611a80b8a225dd13d07676decc3281fe218449e47d6c20cc7ff' 
  AND token = 'NMd4mkjdTeCgm0W3L7QYbRovfoTxahGxDvcBibyz4cI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}