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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb0e841d7eaa2e962c46166869b1a99c0a8864c27c69a98391c82528d6b68b80' 
  AND token = '2mAHmvUidjw6Ed7dtWkuiKSPm6pxbvsn3bqde3G+gTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}