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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f4c99d3aee1d487727cd41bc3564779c810ad1f66b7c650387f62bd56965aa2' 
  AND token = 'rHq7AcA3iHS/w1W0t1GsGdF4NqvTPJHO+2IyS9Co/2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}