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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '349a44aac80756422ac7375b9de91150cce72aa1c43f5fa5e2356b15b2993cac' 
  AND token = '12pOH52VjfRe9iaQQWTe35LCKn0aH9SqhC/UaORM5ZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}