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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be6de33ea4b73e07080aa983310f34e51ba88c5edf67b578aca37614a2beaab4' 
  AND token = '9XznM6MkQDOzvSeT2vgVkyLK+FjA+kVq6mX0q64sAVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}