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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f73d028994e3c0b245f670226b8dbcb8699c78781c8343a81621dadb884710eb' 
  AND token = 's95fvEYvSYy8tGTw23wJC097XTch0n2271yfCoDRn3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}