SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8042017b7078482296db5ce40321e892f4a45544ecc32d405b15ff7b612bd25' 
  AND token = '5j4NL4n9MMM6bnkJjuAnBja0Wlt4gQMrqbyG6Jrg2PU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}