SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1546c8c84f4b1d70ae0b8456b583ebb3e2d86c3341369463ca499340d8cbbe42' 
  AND token = '5gaIhm2I7WQyXnIGbTXTzKaSIH5LNViRqwZUk+oLrwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}