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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '729699d8886a44acc0e25f8afdc0f843576cd514c52f1ba761bb8e7692f0725c' 
  AND token = '7Q6EvtExc+zE0PMBUstkA3VdHPouk7PnhL26TIU47bE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}