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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7983999794ecff185cd464b9d625e8d609f20c4f8066f75117c03c5b9529c7f' 
  AND token = 'siEA0liYWYgqutHGo0qgTY7k/CAwmIGmzrOdT20DZgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}