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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ad46b644ced683692db256464929d9a5640b64f752ae5b35af7a7a7539eedc8' 
  AND token = 'Se4Voxru22a6usm0WAAvlbmklXGYywwnmU1aySuPaJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}