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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6be036ab9bcddabdc940c319351b2723c7e1d0c5403317b31e86c9a723c9ca29' 
  AND token = '0cz2JGB/ThLXmdcFoar1bfdWvBsWeTL3ZNRJo8YWLGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}