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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72472f5d1fb745c5c4d1d7dc04b92d7acb90ffb0c5e48c214011e4e80d7ef3d7' 
  AND token = 'p1MqK/X0wY4zeuK0hlCUjtt+vcK9aluDOFDoI/+Zqc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}