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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41c331d5501b228ab88aed20e0b5f288f5dd71c2bce4018206ad5c073011cd20' 
  AND token = 'JrrMCPriHlgFT/AiweEG2sQ0Xx2rSZiq+GjZjJcoNf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}