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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be49529b1f71e5d2888d03f7718dcd5818ae3d81d28d8f83f8da3a0de4f5db49' 
  AND token = 'D5anQ7sGuUkrbiYvDAQwJhCLcc24mROMYvQ4cwK7dBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}