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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99bde4abfc6444e30f2203af184b1659a605abb8c7588f0a6568406f6c4c127f' 
  AND token = 'LBh7CSquQj0jt4uR57oLfXCqFLLfFLS6+x0LcZxaztI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}