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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18f23185301eff05bb5f6a0a414ee8c1f5ccc5e83b42f150bc6cac2629322be2' 
  AND token = 'cM2v4OhneKAQV6AntR6Fz4dp6xfm0obR1l5GX708fDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}