SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff861a0cf39bf1ab46852ee51c58a933388f736caae4a012a9caa2f1edfe3cda' 
  AND token = 'k7tcUM1Zdz1Rufi2ZsvjM99v7ewk3kIVGaYoTIjosHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}