SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61defea1bb035c79741471635a3c32f60100a78c6d0e511f19cacd5a1b0250ec' 
  AND token = 'PQOx2Yzd/cejcgp3y2q45MUg9vf331AX2V5quIDqZAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}