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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff708608195dffe3c4c6bc36d5e269a15d212a3113859e1fbb230a019d8a5f80' 
  AND token = 'kFksRD30ou2z0I+mbChhLJ5RfQx4kL1xJ79yKLeG2T4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}