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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '544a2d1ea551922ee97e0fe4775e679f41f3b5451d13ffa517cf0d09a2e24bc5' 
  AND token = 'Bp+oJXyVfDbYDyG6Vk1D7HUSyzKot18j8jeHsrGMAp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}