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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec5f5dfb6887b3c350d0cef0be1900882d9e25b23851e354a8d9de1e42cd753d' 
  AND token = 'zM2OidqTo+SMWjg4HUGJ4XlwTqHBa/bs2tWccMivnQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}