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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce9e7835a26cf0d29b0b639585803434fe1117cb20ecd214c8a2d0eddc61c5c6' 
  AND token = 'OcJ0eCIUfS7xeCKjvKXf3s3YzAr2DiIylW43zvo7LQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}