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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c106491a67a77bb31a9a78734fc80964ec9a9173bed8874ab7e9220efca3bd56' 
  AND token = 'CIjl4idhy0/UmHBNP0u5FUqyoVOXL3GvHWRc5v157iU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}