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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b255b6f20afd15bb528cf8e203ba80092ddf6dd80d8278c4b9318938555d8d56' 
  AND token = 'nOD9fqzpS2DRgSoYVQe8+2T8iEGoJtmsSxCkEDzobVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}