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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '146cfc48de43ceb8dfca0ab1c8ac9bf6eab30e4b36eba190d38797fea8d6181f' 
  AND token = 'WcTbBen3FNNVEv0cQ6RUSMKxkH5umsd2ZB+RBKSKY6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}