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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '549cbaf7f56c73b0370f5d8483dbf0b22ce4fbcb5dc80cd280b81c50b6cbd7d9' 
  AND token = '77Q3R4F4+3oOXQyZLL3Lopb7tenY6S/3BU+ZZPEdzhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}