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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ea4e3bb8f1bf6fb9fb06be349b079718fccbee42eb396641032c20546c070c8' 
  AND token = 'TctRwQEtEQV8TeTbT1dz6Z1x+JiDuDjNk49k3k0qzOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}