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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2199c3aae9bcdc028fc6d80827e76b2d19be526abb1a7038134c7e4c45d2278' 
  AND token = 'qVYOV+Q+Cownk/WClvKx1E9dAXQ3Os2AJGNIdcmbdv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}