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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ed450ed12857710cbd2606f333580317c2da8a19353aae8c9585df9fe97fe83' 
  AND token = 'v/3m/lUR9egB0Kdtpo6/taRgOqxd5XEWQEXAy8Yb+tw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}