SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28b01bf2db88b5c0fd0f58f7dedd6a0c3109bc8d52fcc3166ad782aa336e285f' 
  AND token = 'xyNYX0AFU0wrhpG4VsCShXNCs0omGssEx4ahqltbXGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}