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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43c626c1b58839c1bdcc4c623b427ed27fd3135036c8e2d4da174c258032dfb8' 
  AND token = 'gYBrP6uTA7Rd+WtLL96PXj7zaXb94rdSSVZmzOTz148=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}