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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf956904e3abc5eabc7dfbf21afb22644165863abcc296230a01e0a80edbc339' 
  AND token = 'L/u/w0+n9G/I6ifG7HEtYSTC2JVwl96KF021yKxvE0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}