SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a621f56757a2c40e2cf47d4fe19e0f909a85f54b6564e3a2a2319b8146e7b77' 
  AND token = 'FU9qJ7Bpmn2WUCBhSnMqrL6sMUjA0jlIm+Icvt3ahWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}