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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42497c7438c3c86348112045e359e29efe1ad178cd597fa5d20b00662e4aa7f0' 
  AND token = 'hNbvksC31UcSrscOeWXRZ3EDB9PuUzoZr7s1eU6OU+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}