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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e78cc6a4dbe42fcf52efa8a25b9c6a00210007ae58f5a39b84c34852f3d20d8c' 
  AND token = 'qtN/SrBymMGIwd6XpSDfYifG4+9fuCATJLfnxB+7nTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}