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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27a64e2dd1c2295d8e7491b4068002433933deefe62a60fba6c505fb34b540d6' 
  AND token = '7e9/AHt/pJKRx9NWAwcjLOk8j6NMKr4BijP2y8OVbbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}